Clearance of theophylline is decreased by
WebMar 16, 2024 · Mildly decreased renal function. 60 – < 90. 10 mg once daily. Moderately decreased renal function. 30 – < 60. ... the dose will have to be adjusted on an individual basis taking into account the renal clearance, age and body weight of the patient. ... notably with pseudoephedrine or theophylline (400 mg/day). ... WebFifty three subjects (31 normal volunteers and 22 patients with asthma) between the ages of 20 and 87 years had their theophylline clearance measured. Volume of distribution (V) …
Clearance of theophylline is decreased by
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WebThe clearance of theophylline is decreased by an average of 30% in healthy elderly adults (>60 yrs) compared to healthy young adults. Theophylline clearance may be … WebFebrile illnesses may result in decreased theophylline clearance, whereas tobacco and marijuana smoking result in accelerated clearance. Side-effects of theophylline are often dose dependent and include anorexia, nausea, emesis and headache.
WebThe pharmacokinetics of theophylline and dyphylline in four rabbits were investigated following intravenous injection. Each rabbit received theophylline (10 mg/kg) first then dyphylline (25 mg/kg) two weeks afterwards as an intravenous bolus injection. The serum concentration-time data for both theophylline and dyphylline were best fitted to the two … WebTheophylline: Clearance decreased; reduce theophylline dose by one-third (5.8). Warfarin: Plasma concentrations increased and prothrombin times prolonged; monitor …
WebDosage Guidelines for Theophylline in Children Older Than 6 Months and Adults Who Have No Risk Factors for Decreased Theophylline Clearance. Transient effects similar to those of caffeine, such as ... WebTotal body clearance of theophylline decreased significantly, whereas renal clearance and protein binding did not change. When enoxacin, 800 mg daily, was administered to seven patients with a stable chronic obstructive pulmonary disease, who were on long-term theophylline treatment a significant increase in plasma theophylline concentrations ...
WebTheophylline clearance may decrease in patients with congestive heart failure, acute pulmonary edema, hepatic disease, cor pulmonale, acute hepatitis, hypothyroidism, …
WebCongestive Heart Failure (CHF) Theophylline clearance is decreased by 50% or more in patients with CHF. The extent of reduction in theophylline clearance in patients with CHF appears to be directly correlated to the … port vs richmond ticketsWebEnter the email address you signed up with and we'll email you a reset link. port vs west coast ticketsWebClearance is markedly decreased in patients with impaired liver function, such as hepatic cirrhosis (see section 4.5). Certain substances, including tobacco and marijuana, have been shown to affect the hepatic clearance of theophylline, thereby affecting its serum concentration (see section 4.5). It is port vs power portironing board table with storageWebNov 2, 1983 · The elimination of theophylline (clearance, half-life) was investigated in 50 patients with chronic congestive heart failure (grade III/IV) and in 20 controls. The cardiac diagnosis was based on clinical and hemodynamic parameters. Patients with congestion of the liver showed a significant reduction …. port vs switchWebOct 6, 2024 · Theophylline clearance is decreased by 50% in hepatic insufficiency. Frequent monitoring of serum theophylline concentrations is required. Precautions. CONTRAINDICATIONS: Hypersensitivity to any of the ingredients, theophylline, or ethylenediamine; Consult WARNINGS section for additional precautions. ironing board stationWebAminophylline is a combination of theophylline and ethylenediamine. Ethylenediamine is inactive; it increases the solubility of theophylline in water. ... and to neonates and the elderly, since in all of these circumstances theophylline clearance may be decreased, resulting in increases in serum-theophylline concentrations and serum half-life ... ironing board tsunade