Cyclic pifithrin-a
WebJul 1, 2008 · (PDF) Cyclic Pifithrin-α Sensitizes Wild Type p53 Tumor Cells to Antimicrotubule Agent–Induced Apoptosis 1 Cyclic Pifithrin-α Sensitizes Wild Type p53 Tumor Cells to Antimicrotubule... WebJan 23, 2024 · Pifithrin-α (PFT-α) is a small molecule which has been widely used as a specific inhibitor of p53 transcription activity. However, its molecular mechanism of action …
Cyclic pifithrin-a
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WebThe yellow region in helix 1 is the MRAIL sequence or hydrophobic patch, which contributes to the recognition of some substrates. (PDB 1fin) Cyclin is a family of proteins that … WebCyclic Pifithrin- α hydrobromide is a cyclic analog of pifithrin- α (Cat. No. 1267), a small molecule inhibitor of p53. Prevents dexamethasone -induced cell death in murine …
WebJul 17, 2024 · Cell-based assays in multiwell plates are widely used for radiosensitivity and chemosensitivity assessment with different mammalian cell types. Despite their relative ease of performance, such assays lack specificity as they do not distinguish between the cytostatic (reversible/sustained growth arrest) and cytotoxic (loss of viability) effects of … WebCyclic Pifithrin-α hydrobromide has been used as p53 inhibitor to study its role in cigarette smoke−induced apoptosis of pulmonary endothelial cells. [ 1] Packaging 5, 10 mg in …
WebCyclic Pifithrin-α hydrobromide is the hydrobromide salt form of Cyclic Pifithrin-α, which is a transcriptional inhibitor of p53. CAS No. 511296-88-1 Selleck's Cyclic Pifithrin-α … WebCyclic Pifithrin-α hydrobromide Tocris Bioscience a Bio-Techne Brand Catalog # 3843 Citations (1) COA / SDS Catalog # Availability Size / Price Qty 797-B2-025 In Stock 25 ug / $394.00 Add To Cart Print Quote Bulk Order Key Product Details Order Information Bio-Techne Corporation tel: (800) 343-7475 (free phone) tel: (612) 379-2956
WebBiological description. Stable, cell-permeable analog of pifithrin-α ( ab120478 ). Inhibits p53-mediated apoptosis and p53-dependent gene transcription. Prevents …
WebJul 1, 2008 · In this study, we used cyclic pifithrin-α, a transcriptional inhibitor of p53, to further investigate the relevance of p53 function in the response of tumor cells to … organizational design and structure pptWebCyclic Pifithrin-alpha Hydrobromide 98.0 %, TCI America Fisher Scientific Fisher Scientific Fisher Healthcare Fisher Science Education Sign Up for Email Help & Support … how to use mob abilities in the morph modWebMay 10, 2016 · In this study, we optimized reprogramming approaches for hUCs with very poor proliferation. We report here that a compound cocktail containing cyclic pifithrin-a (a P53 inhibitor), A-83-01, CHIR99021, thiazovivin, NaB, and PD0325901 significantly improves the reprogramming efficiency (170-fold more) for hUCs. In addition, we showed … organizational departmentsWebCyclic Pifithrin-alpha is a reversible and cell-permeable inhibitor of p53, which plays a crucial role in apoptosis, angiogenesis, and genomic stability. The cyclic form is the more stable and less cytotoxic version of the molecule. It is reported to be capable of increasing the efficiency of inducing pluripotent stem cells. how to use mo2 skyrim seWebCyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α a small molecule inhibitor of p53. It reversibly inhibits p53-dependent transactivation of p53-responsive genes and … how to use moar swords data packWebKey features and details. Cell-permeable transcriptional p53 inhibitor. CAS Number: 60477-38-5. Purity: > 99%. Soluble in DMSO to 10 mM. Form / State: Solid. how to use mob ability in morph modhttp://shiji.cnreagent.com/s/sv253508.html howtousemobile26