Web12 mei 2024 · RNA-antisense pulldown identified nucleolysin TIAR, a translational repressor, to bind to a 71-nt hairpin within PHAROH, sequestration of which increases c-MYC translation. In summary, our data suggest that PHAROH regulates c-MYC translation by sequestering TIAR and as such represents a potentially exciting diagnostic or … WebAnti-TIAR Antibody, clone 3E6 Anti-TIAR, clone 3E6 Antibody, Cat. No. MABF2662, is mouse monoclonal antibody that targets TIAR and has been tested for use in ELISA, …

RCSB PDB - 2CQI: Solution structure of the RNA binding domain …

WebThis subgroup corresponds to the RRM3 of nucleolysin TIAR, also termed TIA-1-related protein, a cytotoxic granule-associated RNA-binding protein that shows high sequence similarity with 40-kDa isoform of T-cell-restricted intracellular antigen-1 (p40-TIA-1). TIAR is mainly localized in the nucleus of hematopoietic and nonhematopoietic cells. WebTIAR is mainly localized in the nucleus of hematopoietic and nonhematopoietic cells. It is translocated from the nucleus to the cytoplasm in response to exogenous triggers of … briefcase\u0027s 6j

TIAL1 Gene - GeneCards TIAR Protein TIAR Antibody

WebNucleolysin TIA1 Using whole-exome sequencing, an autosomal dominant mutation (p. 362L) in the RNA-binding protein TIA1 (T-cell-restricted intracellular antigen-1) was … WebTIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 [ (cattle)] Web15 sep. 1992 · Although the RNA-binding domains of TIA-1 and TIAR share greater than 85% amino acid homology, their carboxyl-terminal auxiliary domains are only 51% … briefcase\\u0027s 6j