Phf1 protein
WebPHF1 is part of cluster 72 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore … WebJul 28, 2014 · PHF1 and total Tau antibodies were used to blot the Tau transgenic lysates for correlation with TFEB levels. E, F. Quantification of relative band intensities in WT (E) or Tau (F) mice. Student's t-test shows that TFEB protein levels are significantly increased in WT + TFEB vs WT (**P = 0.0026) and in Tau + TFEB vs Tau (*P = 0.047).
Phf1 protein
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WebTarget Information. This gene encodes a protein with significant sequence similarity to Drosophila Polycomblike. The encoded protein contains a zinc finger-like PHD (plant homeodomain) finger which is distinct from other classes of zinc finger motifs and which shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong ... Web1. former designation for biotin; 2. vitamin B12 analogue or precursor; 3. a glycoprotein that regulates the activity of complement factor C3b; a deficiency results in the lack of …
WebLiu R et al. PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote … WebShowing subcellular location of PHF1 (MTF2L2, PCL1, TDRD19C).
WebAccording to another report, PHF1 recruits the PRC2 complex at double-strand breaks (DSBs) and inhibits the activity of PRC2 (PubMed:23142980). Regulates p53/TP53 stability and prolonges its turnover: may act by specifically binding to a methylated from of p53/TP53. ... The protein is a component of a histone H3 lysine-27 (H3K27)-specific ... WebJan 31, 2024 · In human cells, the PHD finger Protein 1 (PHF1) which contains Tudor domain is associated with DNA damage repair proteins. PHF1 is recruited to DSB sites depending on Ku that is the sensor for NHEJ. Moreover, depletion of PHF1 sensitizes cells to X-ray induced DNA damage and increases HR frequency [ 39 ].
WebJul 23, 2024 · PHF1 (PHD protein finger 1), also known as polycomb-like protein 1 or hPCI1, is a 567 amino acid member of the PHD finger protein family. Members of the PHD finger …
WebBy immunohistochemistry, S100 protein was negative in all 4 cases, while desmin was positive in 2 cases. In 2 cases, the Illumina TruSight RNA Fusion Panel demonstrated a PHF1::TFE3 and EP400::PHF1 fusion, respectively. In the remaining 2 cases, PHF1 gene rearrangement was confirmed by fluorescence in situ hybridization analysis. runnin sheep book pdfWebJul 13, 2011 · PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR1 (PHF1) is known to regulate the plasma membrane localization of PHT1;1, a high-affinity inorganic phosphate (Pi) transporter in Arabidopsis ( Arabidopsis thaliana ). scdhec chris stoutWebDescription Rabbit monoclonal [EPR14222] to PHF1 Host species Rabbit Specificity This antibody is specific to PHD finger protein 1, not paired helical filaments. Tested applications Suitable for: Flow Cyt (Intra), IHC-P, ICC/IF, WB, IP more details Species reactivity Reacts with: Mouse, Rat, Human Immunogen Synthetic peptide. scdhec checklist for design professionalsWebMar 9, 2024 · PHD finger protein 1, polycomb-like protein 1, t-complex testis-expressed 3. GeneRIFs: Gene References Into Functions. Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. PHF1 is necessary for the accurate alignment of chromosomes and oocyte euploidy, as well for the regulation of the asymmetric division … runnin through the 7 with my woadiesWebFeb 15, 2024 · Selenium application as sodium selenate was repeatedly shown to have anti-carcinogenic properties by increasing levels of the serine/ threonine protein phosphatase 2A (PP2A) in cancer cells. PP2A has a prominent role in cell development, homeostasis, and in neurons regulates excitability. PP2A, GSK3β and Tau reside together in a complex, … scdhec charleston regional officeWebAug 9, 2024 · The protein levels of PHF1 were significantly lower versus those in paired normal tissues, as indicated by quantification of PHF1 h-scores (Fig. 1C–D ). runnin outta moonlight randy houser lyricsWebIt is a human homolog of the Drosophila protein Polycomb-like protein. PHF1 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. runnin through the 7th with my woadies osu