Web16 Apr 2024 · First-line therapy for advanced non–small-cell lung cancer (NSCLC) that lacks targetable mutations is platinum-based chemotherapy. Among patients with a tumor proportion score for programmed ... Web13 Apr 2024 · The single echinoderm microtubule-associated protein-like 4 (EML4) gene and anaplastic lymphoma kinase (ALK) gene fusion is the most common variant of ALK …
Lung cancer - Treatment - NHS
WebExtensive-disease small cell lung cancer (ED SCLC) is characterized by initial chemosensitivity, followed inevitably by relapse. The optimal role of additional chemotherapy at the time of progression is controversial. We … Web1 May 2013 · The authors added that continuation maintenance chemotherapy is preferable to second-line chemotherapy because the early use of non—cross-resistant therapies may kill more cancer cells prior to ... crazy craft server ip java
NSCLC, long-term survival with neoadjuvant immunotherapy
WebOptions for second-line chemotherapy are determined by the regimen received as first-line therapy and patient PS. Based on guidelines from the NCCN and ASCO, for patients with a PS of ECOG 0–2 initially treated with gemcitabine-based regimens, options for second-line therapy are FOLFOX, FOLFIRI, and 5-FU with liposomal irinotecan. Web30 Mar 2024 · Pooled analyses were conducted with, first-line chemotherapy trials for advanced non-small cell lung cancer (CALGB 9730, 30203, and 30801). Comparisons -- with age 65+ and 70+ years -- were performed for TTF (primary endpoint), reasons for early chemotherapy cessation, grade 3+ adverse events, and overall survival. Web2 Feb 2024 · XPO1 was highly and ubiquitously expressed in SCLC relative to other lung cancer histologies and other tumor types. XPO1 knockout enhanced chemosensitivity, … crazy craft servers for minecraft java